| 细胞凋亡（Apoptosis）是生物体细胞的主动消亡过程，是多细胞有机体调控机体发育、控制细胞衰老、维持内环境稳定的重要机制。细胞凋亡发生过程的启动和进行收到精确调控，具有独特而复杂的信号系统。各种凋亡信号通过信号传导通路传至细胞内，激活靶分子而产生细胞效应，引发细胞凋亡。一般认为，细胞凋亡存在三条主要通路：线粒体通路、内质网通路和死亡受体通路，各通路间相互联系，共同调节细胞凋亡。细胞凋亡的过程大致可以分为以下几个阶段：接受凋亡信号—凋亡调控分子间的相互作用—蛋白水解酶的活化（Caspase）--进入连续反应过程。 ![\"\"](\"http://liankebio.com/public/images/f0/79/d8/973f447b7800927e838ad457e6cfff7d8f4ca7d9.jpg?1468827113#w\")
Novus 提供大量高质量的凋亡信号通路研究相关的抗体，以下是热销产品简介： ![\"\"](\"http://liankebio.com/public/images/2f/3c/cc/b6edb60e80986ae8ce94c2e44ad3c4e6dfb8465a.jpg?1468827125#w\")
Caspase相关抗体蛋白 目录号 种属/类型 交叉反应性 应用 |
Caspase-1 NB100-56565 Mu/Mono Hu, Mu, Rt SW, WB, IHC-P |
Caspase-1 NB100-56564 Rb/Poly Hu, Mu WB, IHC-P |
Caspase-1 AF6215 Gt/Poly Hu SW, WB, ICC/IF |
Caspase-2 NB100-56686 Mu/Mono Hu WB |
Caspase-2 NBP1-71393 Rb/Poly Hu, Mu, Rt WB, ELISA |
Caspase-3 NB100-56708 Mu/Mono Hu, Mu, Rt, Ma SW, WB, ICC/IF, |
Caspase-3 NB100-56709 Mu/Mono Hu IHC-P, IHC-Fr |
Caspase-3 NB500-210 Mu/Mono Hu, Mu, Rt WB, IHC-P |
Caspase-3 NB100-56112 Rb/Poly Hu, Mu, Rt SW, WB, IHC-P |
Caspase 4 NBP1-87681 Rb/Poly Hu SW, WB, IHC-Fr, IHC-P, IP |
Caspase 5 NBP1-87682 Rb/Poly Hu ICC/IF, IHC-P |
Caspase-6 NB100-56114 Rb/Poly Hu, Mu, Rt, Ca ICC/IF, IHC-P |
Caspase-6 NBP2-26417 Mu/Mono Hu WB, ICC/IF, IHC-Fr, |
Caspase-7 NB100-56529 Mu/Mono Hu, Mu, Rt IHC-P, IP |
Caspase-7 NB100-56115 Rb/Poly Hu, Mu, Rt, Ge IHC-P |
Caspase-7 NB500-206 Mu/Mono Hu, Mu, Rt WB, IHC-P |
Caspase-8 NB100-56527 Mu/Mono Hu, Pm WB, IHC-Fr, IHC-P, IP |
Caspase-8 NBP1-05123 Rb/Poly Hu, Mu, Rt WB, IHC-Fr, IHC-P, IP |
Caspase-8 AF1650 Rb/Poly Hu, Mu SW, WB |
Caspase-9 NB500-209 Mu/Mono Hu WB, ICC/IF, IHC-P |
Caspase-9 NB100-56118 Rb/Poly Hu, Mu, Rt, Ca, Ge IHC-Fr, IHC-P, IP, Flow |
Caspase-9 NB100-56119 Rb/Poly Hu, Mu, Rt, Ca, Ge SW WB, IHC-Fr, IHC-P, IP |
Caspase-9 NB100-56366 Rb/Poly Hu, Mu, Rt WB |
Caspase-10 NB100-56123 Rb/Poly Hu, Mu, Rt, Ca WB, IHC-P, IP |
Caspase-10 NB100-56125 Rb/Poly Hu WB, IHC-P, IP |
Caspase-10 MAB834 Mu/Mono Hu WB |
Caspase-11 NB120-10454 Rt/Mono Mu WB,ELISA,ICC/IF |
Caspase-11 NBP1-45453 Rb/Poly Mu, Rt WB |
Caspase-12 NBP2-24618 Rb/Poly Hu WB |
Caspase-12 AF1456 Rb/Poly Mu, Rt WB |
Caspase-13 NBP1-76812 Rb/Poly Hu, Mu, Rt WB, ELISA, IHC-P |
Caspase-14 NB100-56126 Rb/Poly Hu, Mu, Rt, Ca WB, IHC-P, IP |
Caspase-14 NB100-56718 Mu/Mono Hu, Mu WB, Flow |
![\"\"](\"http://liankebio.com/public/images/8f/c6/80/756e94a2ada2af77bcc8af56cc4299f768e874c0.jpg?1468827138#w\")
Caspase抑制剂 抑制剂 目录号 抑制靶点 应用 |
Z-IETD-FMK NBP2-29397 Caspase 8 Func, B/N |
Z-LEHD-FMK NBP2-29398 Caspase 9 Func, B/N |
Z-DEVD-FMK NBP2-29396 Caspase 3/7 Func, B/N |
Q-VD-OPH NBP2-29391 Broad-spectrum Func, B/N |
Boc-D-FMK NBP2-29395 Broad-spectrum Func, B/N |
Z-VAD-FMK NBP2-29392 Broad-spectrum Func, B/N |
Z-FA-FMK NBP2-29384 Cathepsins B & L (FMK Inhibitors Control) Func, B/N |
Bcl2家族蛋白抗体 蛋白 目录号 种属/类型 交叉反应性 应用 |
Bcl-2 NB100-56101 Rb/Poly Hu, Mu, Rt, Ca WB, IHC-Fr, IHC-P, IP |
Bcl-2 NBP2-15200 Mu/Mono Hu WB, ELISA, Flow, IP，ICC/IF |
Bcl-2 AF810 Gt/Poly Hu, Mu SW, WB, IHC-P, IP |
Bcl-2 [p Thr56] NB100-92483 Rb/Poly Hu WB, ICC/IF, IHC-P |
Bcl-2 [p Ser70] NB100-92482 Rb/Poly Hu, Mu, Rt WB, IHC-P, IP |
BCL2A1/BFL-1 NB100-56070 Rb/Poly Hu, Mu, Rt, Ge WB, IHC-Fr, IHC-P, IP |
BCL2A1/BFL-1 MAB851 Rt/Mono Mu WB |
BCL2L10/BCL-B NBP1-31681 Rb/Poly Hu WB, ICC/IF, IHC-P |
Bcl-W AF824 Rb/Poly Hu, Mu WB |
Bcl-W AF8241 Gt/Poly Hu, Mu IHC-P |
Bcl-xL NB100-56104 Rb/Poly Hu, Mu, Rt WB, IHC-Fr, IHC-P, IP |
Bcl-xL NBP2-32917 Mu/Mono Hu, Mu, Rt, Po WB, ELISA, Flow, IP，ICC/IF |
Bcl-xL [p Ser62] NB100-92484 Rb/Poly Hu, Mu, Rt WB, IHC-P |
Mcl-1 NB100-56146 Rb/Poly Hu WB, IHC-P, IP |
Mcl-1 MAB828 Mu/Mono Hu WB, IHC-P |
![\"\"](\"http://liankebio.com/public/images/55/df/8f/3a2bc0f93af46edcec7589a1540f3adcae0d6050.jpg?1468827151#w\")
凋亡信号通路相关抗体 蛋白 目录号 种属/类型 交叉反应性 应用 |
APAF-1 NB100-56074 Rb/Poly Hu, Mu, Rt, Ge WB, ICC/IF, IHC-Fr,IHC-P, IP |
APAF-1 MAB868 Mu/Mono Hu WB |
cIAP (pan) MAB3400 Mu/Mono Hu, Mu SW, WB |
cIAP-1 NBP2-27190 Rb/Poly Hu, Mu, Rt, Ca WB, IHC-Fr, IHC-P, IP |
cIAP-2 NBP1-27972 Rb/Poly Hu SW, WB, ICC/IF, |
Cytochrome c NB100-56503 Mu/Mono Hu, Mu, Po WB, Flow, ICC/IF, IHC-P |
Cytochrome c NBP2-24872 Mu/Mono Hu, Mu, Rt B/N, IHC-Fr, IP |
FADD NBP2-16406 Rb/Poly Hu WB, ICC/IF, IHC-P |
Fas Ligand NB100-77833 Mu/Mono Hu WB, Flow, ICC/IF, IP |
NAIP MAB829 Mu/Mono Hu WB, IHC-P |
PARP NB100-56599 Mu/Mono Hu WB, Flow |
RIPK1/RIP1 NBP2-24739 Rb/Poly Hu WB |
ROCK1 NB100-56596 Mu/Mono Hu, Mu, Rt, WB, ICC/IF |
ROCK2 AF4790 Gt/Poly Hu, Mu, Rt WB |
SMAC/Diablo NB100-56311 Rb/Poly Hu WB, ICC/IF, IHC-P |
Survivin NB500-238 Mu/Mono Hu, Mu, Rt WB, ELISA, Flow,ICC/IF |
TRADD NB100-56169 Rb/Poly Hu WB, IHC-P, IP |
TRAF-2 NB100-56173 Rb/Poly Hu WB, Flow, ICC/IF,IHC-P, IP |
TRAF-2 NB100-56715 Mu/Mono Hu WB, IHC-P |
TRAIL/TNFSF10 NB100-56518 Mu/Mono Hu WB, IHC-P |
TRAIL R1/DR4 NB100-56747 Mu/Mono Hu SW, WB, Flow, ICC/IF |
TRAIL R2/DR5 NB100-56618 Rb/Poly Hu WB, Flow, ICC/IF,IHC-P |
Ubiquitin NB300-130 Mu/Mono Hu, Mu, Rt, WB, ELISA, ICC/IF,IHC-Fr |
XIAP NB100-56183 Rb/Poly Hu, Mu, Rt WB, IHC-P, IP |
XIAP AF8221 Mu/Mono Hu, Mu, Rt SW, WB, IHC-P |
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